The master molecule
of longevity.
NAD+ levels decline by up to 50% by your 40s. IV delivery restores them directly at the cellular level — bypassing the absorption limits of oral supplements entirely, with effects on energy, clarity and vitality that are hard to achieve any other way.
Every drip at Maddog is formulated by Dr. Du Plessis and administered by Sister Wren Kobus — a SANC-registered nurse with 20+ years in wellness and 6 years in Emergency Room care — following a proper clinical assessment.
Restore. Repair. Optimise.
NAD+ IV therapy addresses longevity, anti-ageing, skin radiance and cognitive performance at the cellular level. These are the protocols used by wellness leaders worldwide — now available in Ballito, supervised by our clinical team.
"NAD+ is often referred to as the master molecule of longevity. Its levels decline with age, stress and illness — but IV delivery restores them directly at the cellular level, bypassing the absorption limitations of oral supplementation entirely."
Glutathione Glow IV
Brighten · Detox · Radiate
Glutathione is your body's master antioxidant — produced naturally, but depleted rapidly by stress, ageing, alcohol, poor sleep and environmental toxins. Delivered intravenously, it reaches the skin, liver and cells at concentrations impossible orally. The skin-brightening effect is one of its most visible benefits.
Benefits
- Visibly brightens and evens skin tone
- Reduces hyperpigmentation and dark spots
- Powerful liver detox and protection
- Slows oxidative ageing at a cellular level
- Boosts energy and immune resilience
Best for: Skin brightening, anti-ageing, liver health, frequent drinkers, those with dull or uneven skin tone
NAD+ IV
Cellular Energy · Longevity · Vitality
NAD+ (Nicotinamide Adenine Dinucleotide) is a coenzyme present in every living cell, essential for energy production, DNA repair and cellular communication. By your 40s, NAD+ levels have declined by up to 50%. IV NAD+ restores these levels rapidly, with effects on energy, clarity and physical vitality that are difficult to achieve any other way.
Benefits
- Dramatically boosts cellular energy production
- Supports DNA repair and genomic stability
- Improves cognitive function and memory
- Anti-ageing at the mitochondrial level
- Reduces fatigue, improves mood and motivation
Best for: Anti-ageing, fatigue, cognitive decline, post-addiction recovery, anyone over 35 seeking sustained vitality
NAD+ Energy
Single Session · Maximum Energy Output
A higher-dose NAD+ formulation with an energy-amplifying co-factor blend. Designed for those who need to perform at their peak — physically and mentally — for sustained periods. The effects are felt during the infusion and continue building over the following 24–48 hours.
Benefits
- Maximum energy and mental clarity
- Enhanced athletic performance and endurance
- Accelerates recovery between training sessions
- Supports hormonal balance and stress resilience
- Profound improvement in mood and motivation
Best for: Pre-competition, high-performance blocks, executive peak performance, overtraining recovery
Cognitive IV
Focus · Clarity · Mental Performance
Formulated to support brain health and cognitive function — delivering phospholipids, B-vitamins, amino acids and antioxidants that cross the blood-brain barrier more effectively via IV. Clients report sharper focus, faster recall and reduced mental fatigue within hours of infusion.
Benefits
- Enhances focus, concentration and mental stamina
- Reduces brain fog and cognitive fatigue
- Supports neurotransmitter synthesis
- Neuroprotective — reduces oxidative stress in brain tissue
- Improves verbal fluency and memory recall
Best for: Professionals, students, executives, anyone experiencing brain fog, cognitive decline or high mental demand
NAD+ Anti-Aging
Cellular Renewal · Longevity Protocol
Our most targeted longevity protocol. This NAD+ formulation is combined with sirtuins-activating cofactors and antioxidants to support the cellular repair mechanisms associated with healthy ageing. Recommended as part of a quarterly anti-ageing programme.
Benefits
- Activates sirtuin proteins (longevity genes)
- Reduces biological markers of ageing
- Improves skin elasticity and radiance
- Supports metabolic health and weight management
- Profound improvement in overall vitality and wellbeing
Best for: Anti-ageing programme, longevity focus, anyone 40+ prioritising cellular health and graceful ageing
Bespoke IV Optimisation
Designed Around Your Bloodwork
The most personalised protocol we offer. Following a review of your bloodwork and a clinical assessment with Dr. Du Plessis, a bespoke IV formulation is designed specifically around your deficiencies, your goals and your health status. No assumptions — only what your body actually needs.
What's Included
- Full clinical assessment with Dr. Du Plessis
- Bloodwork review and deficiency mapping
- Custom IV formula designed for your specific needs
- Ongoing protocol adjustment as you progress
- The highest level of personalised IV therapy available
Best for: Anyone seeking maximum results, those with complex health needs, longevity-focused clients, VIP care
Add-on boosters.
Upgrade any IV drip with a targeted add-on, administered as part of your session.
A direct IV push of glutathione — the master antioxidant. Adds detox, skin brightening and immune support to any drip.
Additional compounds added to your drip based on your clinical assessment and specific needs. Priced by compound.
Intramuscular injections.
Fast-absorbing IM injections administered by Sister Wren — ideal when you need targeted results without a full drip session. Neurobian is available on Dr. Du Plessis’s prescription only.
Intramuscular vitamin B12 (methylcobalamin) for energy production, nervous system support and combating fatigue. Quick and effective.
A full B-complex plus vitamin C injection — supports general wellness, immune function, metabolism and stress recovery.
High-potency B1, B6 and B12 formula targeting neuropathy, nerve pain and B-vitamin deficiency. Available on Dr.’s prescription only.
Prescription RequiredWhat to expect.
Your first visit begins with a brief clinical assessment. Sister Wren reviews your health history, goals and any medical conditions to determine the right protocol for you.
Your drip is prescribed by Dr. Du Plessis — either a standard protocol from our range or a bespoke formulation tailored to your bloodwork and needs.
You relax in a comfortable private setting while Sister Wren administers your IV drip. Sessions typically take 30–60 minutes. You are monitored throughout.
Many clients notice effects within hours. For best results, a series of sessions is recommended — your protocol frequency will be advised at assessment.
Sister Amanda "Wren" Kobus
Registered Nurse Practitioner · 20+ Years Wellness Industry · 6 Years Emergency Room
Every IV drip at Maddog is administered personally by Sister Wren — a SANC-registered nurse with over 20 years in the wellness industry, 6 years of Emergency Room experience, and military medical training including active deployments. Her background spans midwifery, psychiatry and community nursing, bringing rare clinical depth to every session.
"All treatments are administered following individual assessment and Dr's prescription, and are tailored to your specific health and wellness needs."
NAD+ IV FAQ.
Your longevity protocol starts with one call.
Not sure which NAD+ dose is right for you? That's exactly what our assessment is for. WhatsApp us or book online — Sister Wren will guide you through it.